Management of Crohn's disease in poor responders to adalimumab
نویسندگان
چکیده
منابع مشابه
Management of Crohn’s disease in poor responders to adalimumab
Anti-tumor necrosis factor therapy with adalimumab is an effective therapy for the induction and maintenance of remission in moderate to severe Crohn's disease. Although a large proportion of patients show a favorable clinical response to adalimumab, therapy failure is common. In this review, we provide a practical overview of adalimumab therapy in patients with Crohn's disease, with a specific...
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Infliximab (IFX) is an effective treatment for inducing and maintaining response in Crohn's disease and ulcerative colitis patients. Some patients present lack of response or loss of response to IFX during maintenance therapy. Empirical management with combination therapy with an immunomodulator, IFX dose escalation, or switching IFX for another antitumor necrosis factor-α drug, mainly adalimum...
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ژورنال
عنوان ژورنال: Clinical and Experimental Gastroenterology
سال: 2014
ISSN: 1178-7023
DOI: 10.2147/ceg.s47627